| Collect
screening compounds |
- email
us for a CD of our screening samples, and get MDL®
Screening Compounds Directory
(over 2'000'000 screening compounds)
We
provide the actual screening samples via our cooperation
with
|
over 120'000 samples |
| Select
compounds by chemical criteria |
- use Reagent
Selector, with Chime (MDL® Chemistry
Rules Interface) scripts |
|
| Select
compounds by biological criteria |
- use the new
biological descriptors from PASS
PASS
(Prediction
of Activity Spectra for
Substances) helps you to screen only a fraction of the samples to
find large number of hits. We have shown that with 1% of the amount of samples,
you find already 20% of the hits. - What does this mean? Instead of screening
5000 compounds it is sufficient to screen only 50 compounds, and you can
be assured to find a large number of hits in this enriched selection.
|
in-silico screening |
| Buy the
compounds |
- use
Symyx® Logistics
to store the entries and to produce the order |
|
| Do the
experiment |
-use Assay
Explorer to record standardized notebook entries.
Assay Explorer
handles
all your information and data needs to do, manage and analyze your experiments.
|
biologist's notebook |
| Produce
reports of your data |
- use the
MDL®Report Manager to produce quickly publishable reports |
|
| Share the
knowledge with the project group or company |
-use ChemBio
as a turn-key application to share information among chemists and
biologist.
ChemBio, is a storage and retrieval
system for chemical and summary biological data. |
affordable company-wide
chemical and biological information system |
| Design your
library |
-
MDL® Notebook supports the expanding role of parallel chemistry, offering tools
for building (reaction paradigm), synthesizing, archiving, and analyzing
combinatorial libraries. |
Supports
robots: Gilson 215, Bohdan RAM, TECAN Genesis |
| Design
your synthetic methodology |
-use
robust methods to synthesize your compounds. SPORE
(Solid
Phase
Organic
REactions)
supplements the other reaction databases
with comprehensive information about reactions on solid support. |
comprehensive
database |
| Buy
building blocks |
-
we offer building building blocks. Have a look at our Building
Block database |
515 compounds |
| Select
compounds by chemical criteria |
- use Reagent
Selector, with Chime
(MDL® Chemistry
Rules Interface) scripts |
|
| Build
your library in the computer |
-use MDL®Central
Library to process reagents into libraries |
|
| Select
compounds by biological criteria |
- use the new
biological descriptors from PASS
PASS (Prediction
of Activity Spectra for
Substances) helps you to screen only a fraction of the samples to
find large number of hits. We have shown that with 1% of the amount of samples,
you find already 20% of the hits. - What does this mean? Instead of screening
5000 compounds it is sufficient to screen only 50 compounds, and you can
be assured to find a large number of hits in this enriched selection.
|
-silico screening |
| Buy the
compounds |
- use SMART
to store the entries and to produce the order |
|
| Do the
experiment |
-use Assay
Explorer to record standardized notebook entries.
Assay Explorer
handles
all your information and data needs to do, manage and analyze your experiments.
|
biologist's notebook |
| Produce
reports of your data |
- use the MDL®Report
Manager to produce quickly publishable reports |
|
| Share the
knowledge with the project group or company |
-use
ChemBio
as a turn-key application to share information among chemists and
biologist.
ChemBio, is a storage and retrieval
system for chemical and summary biological data. |
affordable company-wide
chemical and biological information system |