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What is a Polymorph?
Polymorphism
(materials science), a solid which
shares chemical composition with another material but is composed of a
different crystal lattice or form, often called a polymorph.
...from Wikipedia |
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Problems
Early in discovery API limited; however, extensive
screening required to find the most druggable forms
When
performed manually,
extremely
labor intensive, time consuming, and analytically intensive
Solution
Miniaturize experiments to get more data points from less
material
Run more
experiments in parallel to shorten screening cycle times |